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. 2016 Aug 18;8(23):976–984. doi: 10.4254/wjh.v8.i23.976

Figure 3.

Figure 3

Impact of microRNA-17-5p on free insulin-like growth factor-II protein in HuH-7 cells. HuH-7 cells were transfected with miR-17-5p mimics or inhibitors. The free IGF-II protein was measured in media of mimicked and antagonized HuH-7 cells using an IGF-II ELISA Kit. Free IGF-II protein, measured at λmax = 450, was found to be significantly increased upon mimicking of miR-17-5p expression compared to mock untransfected cells (P = 0.0339), while inhibitors of miR-17-5p showed no effect on the levels of free IGF-II protein levels compared to mock cells. Unpaired t-test was performed. aP < 0.05. IGF-II: Insulin-like growth factor-II; miR-17-5p: MicroRNA-17-5p.