Table 2.
Experiment 1 | ||||||||
N+A Substitution | 0.1N+0.1A | 0.2N+0.3A | 0.4N+1.0A | 0.8N+1.7A | ||||
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FP | 3.13±0.73 | 5.13±0.72 | 6.00±0.90* | 4.63±0.68 | ||||
FN | 4.70±0.70 | 4.90±0.76 | 4.25±0.90 | 4.75±1.00 | ||||
Nicotine Substitution | 0.1N | 0.2N | 0.4N | 0.8N | ||||
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FP | 4.10±0.66 | 5.22±0.64 | 7.27±0.72* | 3.95±0.52 | ||||
FN | 4.40±0.45 | 4.10±1.26 | 4.05±0.57 | 3.60±0.66 | ||||
Alcohol Substitution | 0.1A | 0.3A | 1.0A | 1.7A | ||||
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FP | 2.95±0.47 | 3.10±0.54 | 3.45±0.53 | 2.90±0.43 | ||||
FN | 4.05±0.36 | 2.90±0.62 | 3.65±0.55 | 3.60±0.55 | ||||
Experiment 2 | ||||||||
Var Alone | Saline | 1.0 Var | 3.0 Var | |||||
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FP | 3.12±0.48 | 5.12±0.78 | 3.87±0.76 | |||||
FN | 3.62±0.33 | 3.68±0.70 | 3.87±0.86 | |||||
Experiment 3 | ||||||||
Var + N+A Substitution | Saline | Var (1.0) | ||||||
0.1N+0.1A | 0.2N+0.3A | 0.4N+1.0A | 0.8N+1.7A | 0.1N+0.1A | 0.2N+0.3A | 0.4N+1.0A | 0.8N+1.7A | |
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FP | 2.33±0.72 | 4.05±0.85 | 5.22±0.82 | 2.44±0.46 | 3.66±0.70 | 4.50±0.70 | 4.72±0.45 | 2.77±0.52 |
FN | 3.41±0.56 | 4.25±0.80 | 4.66±1.05 | 2.58±0.66 | 3.50±0.46 | 3.41±1.10 | 3.66±0.84 | 3.66±0.73 |
Var + Nicotine Substitution | Saline | Var (1.0) | ||||||
0.1N | 0.2N | 0.4N | 0.8N | 0.1N | 0.2N | 0.4N | 0.8N | |
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FP | 2.81±0.64 | 7.31±2.39 | 8.12±1.32 | 4.56±0.40 | 4.68±0.90 | 5.68±1.15 | 4.81±0.58 | 3.75±0.63 |
FN | 4.35±0.68 | 4.78±0.82 | 6.21±0.91 | 3.64±0.45 | 3.57±0.50 | 4.57±0.76 | 4.57±0.38 | 5.14±0.97 |
Var + Alcohol Substitution | Saline | Var (1.0) | ||||||
0.1A | 0.3A | 1.0A | 1.7A | 0.1A | 0.3A | 1.0A | 1.7A | |
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FP | 2.21±0.30 | 3.57±0.42 | 4.14±0.53 | 2.78±0.65 | 5.07±1.50 | 4.57±1.02 | 4.42±0.55 | 3.42±0.36 |
FN | 4.43±0.50 | 4.87±0.47 | 4.68±0.66 | 3.56±0.43 | 4.93±0.73 | 6.31±1.07 | 5.12±0.88 | 5.12±0.57 |
denotes significant difference (p < 0.05) from lowest dose or saline.