Table 3. Results of subgroup analyses according to trial and participant characteristics for total cholesterol and LDL-cholesterol.
| Group | No | Net change (95% CI) | P-heterogeneity | I2 (%) | |
|---|---|---|---|---|---|
| Total cholesterol | |||||
| Total | 15 | −0.30 (−0.36, −0.25) | 0.953 | 0 | |
| Baseline | ≥6 mmol/L | 6 | −0.35 (−0.46, −0.23) | 0.872 | 0 |
| <6 mmol/L | 8 | −0.29 (−0.35, −0.23) | 0.789 | 0 | |
| Duration | ≥7 wk | 7 | −0.30 (−0.41, −0.19) | 0.439 | 0 |
| <6 wk | 8 | −0.31 (−0.37, −0.24) | 0.999 | 0 | |
| Stanol or sterol dose | ≥3 g | 6 | −0.29 (−0.35, −0.24) | 0.816 | 0 |
| <3 g | 9 | −0.37 (−0.52, −0.21) | 0.897 | 0 | |
| Diet modification | yes | 8 | −0.31 (−0.37, −0.25) | 0.990 | 0 |
| no | 7 | −0.29 (−0.39, −0.18) | 0.531 | 0 | |
| Intervention | sterol only | 8 | −0.34 (−0.49, −0.19) | 0.931 | 0 |
| stanol only | 9 | −0.31 (−0.36, −0.25) | 0.697 | 0 | |
| Study design | parallel | 9 | −0.31 (−0.37, −0.25) | 0.715 | 0 |
| cross-over | 6 | −0.26 (−0.39, −0.14) | 0.988 | 0 | |
| LDL-cholesterol | |||||
| Total | 14 | −0.30 (−0.35, −0.25) | 0.958 | 0 | |
| Baseline | ≥3.5 mmol/L | 6 | −0.30 (−0.37, −0.23) | 0.925 | 0 |
| <3.5 mmol/L | 6 | −0.28 (−0.36, −0.20) | 0.673 | 0 | |
| Duration | ≥7 wk | 6 | −0.35 (−0.45, −0.25) | 0.843 | 0 |
| <6 wk | 8 | −0.28 (−0.34, −0.23) | 0.949 | 0 | |
| Stanol or sterol dose | ≥3 g | 6 | −0.30 (−0.36, −0.25) | 0.868 | 0 |
| <3 g | 8 | −0.28 (−0.40, −0.15) | 0.818 | 0 | |
| Diet modification | yes | 7 | −0.31 (−0.40, −0.22) | 0.745 | 0 |
| no | 7 | −0.30 (−0.35, −0.24) | 0.909 | 0 | |
| Intervention | sterol only | 8 | −0.27 (−0.39, −0.14) | 0.868 | 0 |
| stanol only | 8 | −0.31 (−0.36, −0.26) | 0.890 | 0 | |
| Study design | parallel | 8 | −0.30 (−0.36, −0.25) | 0.881 | 0 |
| cross-over | 6 | −0.30 (−0.40, −0.20) | 0.761 | 0 | |