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. 2016 Aug 19;6:29176. doi: 10.1038/srep29176

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Copyright © 2016, The Author(s)

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(A) HE staining showed smooth surfaces in human articular cartilage and rough surfaces in OA human articular cartilage. Scale bars, 50 μm. (B) Real-time PCR analysis revealed higher expression of EZH2 mRNA in OA chondrocytes (n = 8) cultivated from OA cartilage sample compared to normal chondrocytes (n = 10). *p < 0.05. (C) A representative comparison of the EZH2 level of human normal and OA chondrocytes by western blot. (D) Quantitative analysis of western blot confirmed a significant upregulation of EZH2 expression in OA chondrocytes compared with normal chondrocytes. Values are means ± SD, *p < 0.05.