Table 2. Univariable logistic regression analysis: predictors of disease occurrence.

Predictor	β	S.E	P value	Exp β (OR)	95%CI for Exp β
Model 1 CRP	1.646	0.225	<0.0001	5.186	3.336–8.063
Model 2 S100A12	0.681	0.108	<0.0001	1.974	1.592–2.443
Model 3 sRAGE	−0.483	0.206	0.019	0.613	0.413–0.924
Model 4 TNF-α	0.019	0.007	0.010	1.024	1.005–1.034
Model 5 Age	−0.051	0.012	<0.0001	0.954	0.927–0.973
Model 6 BMI	−0.650	0.073	<0.0001	0.523	0.452–0.603
Model 7 Systolic BP	−0.081	0.011	<0.0001	0.924	0.903–0.944
Model 8 Fasting blood glucose	−0.009	0.005	0.081	0.992	0.979–1.001
Model 9 Smoking habits	−0.566	0.319	0.076	1.763	0.943–3.291
Model 10 Drinking habits	2.487	0.629	<0.0001	12.02	3.505–41.23

Models parameters: Model 1 CRP: constant: −8.20, −2Log likelihood 185-Chi² < 0.0001, Hosmer and lemeshow test <0.0001, R² (Cox 0.49 and Nagelkerke 0.67). Model 2 S100A12: constant: −1.42, −2Log likelihood 328-Chi² < 0.0001, Hosmer and lemeshow test 0.01, R² (Cox 0.17 and Nagelkerke 0.23). Model 3 sRAGE: constant: 0.206, −2Log likelihood 405-Chi² 0.016, Hosmer and lemeshow test 0.64, R² (Cox 0.019 and Nagelkerke 0.026). Model 4 TNF-α: constant: −0.48, −2Log likelihood 375-Chi² 0.016, Hosmer and lemeshow test 0.07, R² (Cox 0.03 and Nagelkerke 0.04). Model 5 Age: constant: 1.17, −2Log likelihood 392-Chi² 0.002, Hosmer and lemeshow test 0.82, R² (Cox 0.06 and Nagelkerke 0.08). Model 6 BMI: constant: 12.05, −2Log likelihood 170.5-Chi² < 0.0001, Hosmer and lemeshow test 0.88, R² (Cox 0.55 and Nagelkerke 0.73). Model 7 Systolic BP: constant: 8.8, −2Log likelihood 312.1-Chi² < 0.0001, Hosmer and lemeshow test 0.21, R² (Cox 0.24 and Nagelkerke 0.33). Model 8 Fasting blood glucose: constant: 0.66, −2Log likelihood 403.8-Chi² 0.048, Hosmer and lemeshow test 0.86, R² (Cox 0.012 and Nagelkerke 0.017). Model 9 Smoking habits: constant: −0.302, −2Log likelihood 405-Chi² 0.032, Hosmer and lemeshow test 0.001, R² (Cox 0.01 and Nagelkerke 0.02). Model 10 Drinking habits: constant: −0.494, −2Log likelihood 358-Chi² < 0.0001, Hosmer and lemeshow test 0.001, R² (Cox 0.08 and Nagelkerke 0.11).