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. 2016 Aug 19;6:31617. doi: 10.1038/srep31617

Table 2. Meta-analysis of the association between FCGR2A rs1801274 polymorphism and SLE risk.

Population N A vs. G(allele model)
AA vs. AG+GG(recessive model)
AA+AG vs. GG(dominant model)
OR(95%CI) POR Ph OR(95%CI) POR Ph OR(95%CI) POR Ph
Overall 34 0.879(0.819–0.943) 3.31 × 10−4 0.109 0.867(0.784–0.960) 6.14 × 10−3 0.214 0.843(0.739–0.961) 0.011 0.074
Caucasian 12 0.845(0.766–0.932) 8.08 × 10−4 0.439 0.775(0.655–0.917) 3.08 × 10−3 0.522 0.883(0.756–1.032) 0.117 0.427
Asian 15 0.896(0.822–0.977) 0.013 0.543 0.932(0.830–1.046) 0.232 0.658 0.767(0.604–0.975) 0.030 0.179
African 3 0.853(0.642–1.132) 0.271 0.438 0.836(0.428–1.633) 0.601 0.192 0.802(0.515–1.250) 0.331 0.688
Mixed population 1 1.133(0.887–1.448) 0.318 1.144(0.721–1.817) 0.568 1.27(0.844–1.911) 0.252
Non-Caucasian 1 1.259(0.898–1.765) 0.181 1.250(0.674–2.317) 0.479 1.538(0.887–2.666) 0.125
African Americans 2 0.575(0.427–0.774) 2.73 × 10−4 0.422 0.368(0.126–1.078) 0.068 0.100 0.519(0.324–0.831) 6.33 × 10–3 0.786

OR odd ratio, 95%CI confidence interval, POR P value for the test of association, Ph P value for heterogeneity analysis.