Table 3. Meta-analysis of the association between FCGR2B rs1050501 polymorphism and SLE risk.
| Population | N | C vs. T(allele model) |
CC vs. CT+TT(recessive model) |
CC+CT vs. TT(dominant model) |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| OR(95%CI) | POR | Ph | OR(95%CI) | POR | Ph | OR(95%CI) | POR | Ph | ||
| Overall | 12 | 1.236(1.069–1.429) | 0.007 | 0.030 | 1.754(1.422–2.165) | 1.61 × 10−7 | 0.404 | 1.093(0.952–1.255) | 0.205 | 0.140 |
| Asian | 7 | 1.326(1.095–1.604) | 0.006 | 0.065 | 1.784(1.408–2.261) | 1.67 × 10−6 | 0.630 | 1.149(0.957–1.380) | 0.137 | 0.121 |
| Caucasian | 3 | 1.087(0.888–1.331) | 0.420 | 0.812 | 2.055(1.106–3.817) | 0.023 | 0.587 | 1.019(0.812–1.279) | 0.872 | 0.592 |
| African | 1 | 1.749(1.153–2.655) | 0.009 | — | 2.369(1.198–4.685) | 0.013 | — | 1.777(0.907–3.479) | 0.094 | — |
| African-American | 1 | 0.769(0.537–1.099) | 0.149 | — | 0.745(0.353–1.569) | 0.438 | — | 0.733(0.467–1.152) | 0.178 | — |
OR odd ratio, 95%CI confidence interval, POR P value for the test of association, Ph P value for heterogeneity analysis.