Table 4. Meta-analysis of the association between FCGR3A rs396991 polymorphism and SLE risk.
| Population | N | T vs. G(allele model) |
TT vs. TG+GG(recessive model) |
TT+TG vs. GG(dominant model) |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| OR(95%CI) | POR | Ph | OR(95%CI) | POR | Ph | OR(95%CI) | POR | Ph | ||
| Overall | 26 | 1.17(1.059–1.291) | 0.002 | 0.000 | 1.263(1.123–1.421) | 9.62 × 10−5 | 0.003 | 1.114(0.933–1.331) | 0.232 | 0.004 |
| Caucasian | 9 | 1.259(1.012–1.566) | 0.039 | 0.000 | 1.394(1.087–1.789) | 9.05 × 10−3 | 0.008 | 1.187(0.830–1.699) | 0.347 | 0.004 |
| Asian | 13 | 1.152(0.999–1.328) | 0.051 | 0.004 | 1.211(1.022–1.434) | 0.027 | 0.036 | 1.164(0.884–1.533) | 0.280 | 0.049 |
| African-American | 1 | 1.022(0.880–1.186) | 0.776 | — | 1.053(0.861–1.287) | 0.617 | — | 0.972(0.712–1.327) | 0.858 | — |
| Mixed population | 1 | 1.308(1.029–1.662) | 0.028 | — | 1.585(1.122–2.239) | 9.05 × 10−3 | — | 1.172(0.761–1.804) | 0.471 | — |
| Non-Caucasian | 1 | 0.903(0.649–1.258) | 0.548 | — | 1.049(0.656–1.677) | 0.843 | — | 0.636(0.336–1.204) | 0.164 | — |
| African | 1 | 1.196(0.616–2.324) | 0.597 | — | 1.899(0.638–5.654) | 0.249 | — | 0.750(0.184–3.060) | 0.688 | — |
OR odd ratio, 95%CI confidence interval, POR P value for the test of association, Ph P value for heterogeneity analysis.