Fig. 11.

Supramolar glutamine supplementation partially rescued ATM activity loss induced reduction of BDNF expression. Wild type primary neurons DIV14 were grown in medium containing 0 mM, 2 mM or 8 mM glutamine for 3 days and collected for gene expression analysis. a Quantification of the BDNF common exon by real-time PCR. b BDNF exon 2, 3 and 4 expression levels measured by RT-PCR