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. 2016 Aug 19;11:116. doi: 10.1186/s13023-016-0493-0

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Flow chart of screened patients with exclusion criteria and final size of study population. ASSD: Argininosuccinate synthetase deficiency, ASLD: Argininosuccinate lyase deficiency, CPS1D: Carbamoyl phosphate synthetase 1 deficiency, HE: Hyperammonemic event, N: Number, OTCD: Ornithine transcarbamylase deficiency, SELICA: Safety & Efficacy of Liver Cell Application, study on liver cell transplantation as treatment option for severe metabolic disorders in patients with UCDs. *These patients would have been eligible for this study but were only recorded on the screening log and not documented in the database