Figure 2.
spätzle mutants show reduced resistance to ethanol in a recovery from ethanol sedation assay. Age-matched females are placed in vials and exposed to ethanol vapor until sedated, and then animals are allowed to recover in a humidified air stream. 0 minutes denotes the beginning of the recovery. A) spätzle-null transheterozygotes recover from sedation more slowly than Canton S wild-type control animals (***, p<0.0001). B) Heterozygotes carrying a null allele of spätzle and a wild type chromosome recover from sedation more slowly than Canton S wild-type control animals (***, p<0.0001).