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. 2015 Dec 9;7(15):19445–19467. doi: 10.18632/oncotarget.6523

Figure 9. Expression of progranulin and proMMP-12 in AML cell lines and effect of NGR-peptide-1 on their expression in U937 cells.

Figure 9

(A) Cell lysates from HL-60, THP-1, U937 and NB4 cells were examined for progranulin, proMMP-12 and actin expression in an immunoblot assay. (B) U937 cells were treated for 10 min with 50 μM NGR-peptides after a 30 min pretreatment with 1 mM BAPTA or NAC. Lysates were then western blotted with antibodies against progranulin, MMP-12 (active and latent forms) and actin. One of three representative experiments is shown.