Table 2. Cox proportional hazards model for ypN+ patients stratified by age.

	HR	95%CI	P
Age < 73 years
Histologic grade
Well	1.316	0.315–5.503	0.707
Moderate	1
Poor/Undifferentiated	2.395	1.336–4.295	0.003
Unknown	0.565	0.134–2.383	0.437
Chemotherapy regimens
5-FU	1
Oxaliplatin	0.449	0.225–0.899	0.024
Age ≥ 73 years
ypN category
ypN1a	1
ypN1b	0.951	0.444–2.036	0.898
ypN2a	1.818	0.940–3.516	0.076
ypN2b	3.217	1.484–6.974	0.003
Year of diagnosis
1992–1996	39.044	4.084–373.260	0.001
1997–2000	2.237	0.944–5.304	0.068
2001–2004	.920	0.451–1.878	0.820
2005–2008	1
HCC risk score
1st quartile	1
2nd quartile	0.661	0.303–1.441	0.298
3rd quartile	0.780	0.347–1.756	0.548
4th quartile	2.361	1.206–4.624	0.012
Chemotherapy regimens
5-FU	1
Oxaliplatin	1.484	0.701–3.142	0.303

Abbreviation: 5-FU, 5-fluorouracil; CI, Confidential intervals; HCC, Hierarchical Condition Categories.