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. 2016 Feb 21;7(15):19680–19692. doi: 10.18632/oncotarget.7547

Figure 5. Effect of ZFX knockdown on the growth of CRC cell xenografts.

Figure 5

(A) Representative images of harvested tumors from nude mice subcutaneously injected with NC or ZFX KD SW620 and SW480 cells. Tumor sizes were decreased after ZFX knockdown. (B) Tumor volumes (upper panel) and weights (lower panel) were decreased after ZFX knockdown (p < 0.05). (C) Representative immunostaining of the Ki-67 proliferation marker in NC and ZFX KD tumors (left panel, 400× magnification). Numbers of Ki-67 positive cells were reduced in ZFX KD tumors (right panel) (p < 0.05).