Table 3. Univariate and multivariate Cox Regression analyses of overall and disease-free survivals of HCC patients after liver transplantation.

Factors	Overall survival				Disease-free survival
	Univariate HR (95% CI)	P	Multivariate HR (95% CI)	P	Univariate HR (95% CI)	P	Multivariate HR (95% CI)	P
Sex (Male vs Female)	1.57(0.43-5.72)	0.495	N/A		1.47(0.40-5.35)	0.559	N/A
Age (<=55 yr vs <55 yr)	0.67(0.22-2.06)	0.487	N/A		0.68(0.22-2.08)	0.501	N/A
Serum AFP (>20ng/ml vs <=20ng/ml)	1.55(0.52-4.60)	0.433	N/A		1.55(0.52-4.61)	0.432	N/A
Tumor size (>5cm vs <=5cm)	0.05(0.00-2884)	0.584	N/A		0.05(0.00-2944)	0.585	N/A
Tumor number (>3 vs <=3)	1.86(0.57-6.05)	0.302	N/A		1.89(0.58-6.13)	0.291	N/A
Vascular permeation (Yes vs No)	1.76(0.54-5.77)	0.351	N/A		1.88(0.57-6.16)	0.298	N/A
pTNM stage (Advanced vs Early)	7.24(0.94-56.13)	0.058	N/A		7.46(0.96-57.79)	0.054	N/A
Differentiation (Poor vs Well)	1.34(0.17-10.60)	0.780	N/A		1.34(0.17-10.60)	0.780	N/A
UCSF criteria (Beyond vs Within)	2.26(0.76-6.74)	0.142	N/A		2.32(0.78-6.91)	0.130	N/A
Milan Criteria (Beyond vs Within)	2.62(0.86-8.02)	0.091	N/A		2.76(0.90-8.45)	0.075	N/A
Type of LT (DDLT vs LDLT)	0.95(0.21-4.29)	0.947	N/A		0.89(0.20-3.99)	0.874	N/A
Graft size (>60% vs <=60%)	1.27(0.39-4.12)	0.694	N/A		1.18(0.36-3.82)	0.788	N/A
Let7C (High vs Low)	1.55(0.51-4.75)	0.440	N/A		1.58(0.52-4.82)	0.426	N/A
miR-21 (High vs Low)	1.35(0.45-4.03)	0.587	N/A		1.42(0.48-4.22)	0.532	N/A
miR-23b (High vs Low)	2.54(0.56-11.45)	0.227	N/A		2.49(0.55-11.22)	0.236	N/A
miR-27b (High vs Low)	2.90(0.89-9.43)	0.076	N/A		2.93(0.90-9.52)	0.074	N/A
miR-122 (High vs Low)	4.61(1.27-16.76)	0.020*	7.24(0.56-93.42)	0.129	4.83(1.33-17.56)	0.017*	5.47(0.58-51.77)	0.138
miR-125b (High vs Low)	2.18(0.67-7.07)	0.196	N/A		2.29(0.71-7.45)	0.167	N/A
miR-148a (High vs Low)	3.70(1.02-13.43)	0.047*	0.45(0.03-6.25)	0.548	3.85(1.06-14.00)	0.041*	0.43(0.02-7.57)	0.561
miR-151p-5p (High vs Low)	2.48(0.68-9.01)	0.169	N/A		2.47(0.68-8.97)	0.170	N/A
miR-192 (High vs Low)	4.93(1.09-22.27)	0.038*	0.67(0.05-8.68)	0.760	4.94(1.09-22.31)	0.038*	0.50(0.03-7.50)	0.618
miR-195 (High vs Low)	1.88(0.24-14.48)	0.544	N/A		1.99(0.26-15.28)	0.510	N/A
miR-199a-3p (High vs Low)	1.05(0.34-3.23)	0.927	N/A		1.15(0.38-3.53)	0.803	N/A
miR-215 (High vs Low)	3.06(0.94-9.97)	0.063	N/A		3.30(1.02-10.73)	0.047*	2.13(0.31-14.71)	0.445
miR-1246 (High vs Low)	9.32(2.06-42.19)	0.004**	10.24(1.39-75.67)	0.023*	9.20(2.04-41.54)	0.004**	10.12(1.45-70.47)	0.020*
miR-1290 (High vs Low)	3.76(1.23-11.49)	0.020*	0.77(0.20-3.05)	0.712	3.86(1.26-11.84)	0.018*	0.88(0.24-3.43)	0.851

^*p<0.05;

^**p<0.01.