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. 2016 Feb 23;7(15):19850–19862. doi: 10.18632/oncotarget.7628

Figure 3.

Figure 3

A. Methylation levels of XRCC3 and XRCC5 in B[a]P-treated HPV16-positive and -negative lung cancer lines. B. XRCC3 and XRCC5 promoter hypermethylation and C. mRNA expression in response to the B[a]P treatment after knockdown or transfection of HPV16 E6 in HPV-positive and HPV-negative lung cancer cells. D. Representative protein levels of DNA methylation-associated genes, including DNMT1, DNMT3b, and HDAC, analyzed by Western blotting in HPV-positive and -negative lung cancer cell lines after HPV16 E6 knockdown or transfection.