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. 2016 Feb 23;7(15):19850–19862. doi: 10.18632/oncotarget.7628

Figure 4.

Figure 4

A. XRCC3 and XRCC5 promoter methylation and B. XRCC3 and XRCC5 gene expression levels in 5′-AZA-treated HPV-positive and -negative lung cancer cells. C. Representative protein levels of DNA methylation-associated genes, including DNMT1, DNMT3b, and HDAC, analyzed by Western blotting in HPV-positive or -negative lung cancer cell lines after p53 or HPV 16 E6 transfection. D. Promoter methylation and E. mRNA levels of XRCC3 and XRCC5 in p53-transfected HPV-positive (TL-1) lung cancer cells.