Table 2. XRCC3, XRCC5, BPDE-like DNA adduct levels, and EGFR/p53 mutation in lung tumor tissues of lung cancer patients.
| Gene | p53 | EGFR | ||||
|---|---|---|---|---|---|---|
| Wild type | Mutant type | Wild type | Mutant type | |||
| XRCC3 | ||||||
| Low | 19 | 16 | 15 | 20 | ||
| High | 46 | 19 | 40 | 25 | ||
| P value | 0.125 | 0.093 | ||||
| XRCC5 | ||||||
| Low | 17 | 18 | 12 | 23 | ||
| High | 48 | 17 | 43 | 22 | ||
| P value | 0.016 | 0.003 | ||||
| XRCC3/DNA adduct levels | ||||||
| Low/low | 9 | 0 | 7 | 2 | ||
| Low/high | 10 | 16 | 8 | 18 | ||
| High/low | 15 | 8 | 19 | 4 | ||
| High/high | 31 | 11 | 21 | 21 | ||
| P value | 0.001 | 0.001 | ||||
| XRCC5/DNA adduct levels | ||||||
| Low/low | 12 | 3 | 9 | 6 | ||
| Low/high | 5 | 15 | 3 | 17 | ||
| High/low | 12 | 5 | 17 | 0 | ||
| High/high | 36 | 12 | 26 | 22 | ||
| P value | 0.001 | <0.0001 | ||||