Table 1. Schematic representation of the morphometric parameters measured and how the results are stated in the paper.

Parameter	Low		High
	Stated in the text	Schema	Stated in the text	Schema
Quantity
Density	Low density		High density
Stained area (SA)	Low SA		High SA
Relative density/SA of blood vessels corresponding to a given segment compared with the total vascularization	Low proportion of blood vessels		High proportion blood vessels
Size
Area	Small		Large
Length	Short		Long
Width	Thin		Thick
Perimeter	Small		Large
Shape
Aspect1	Round		Ovoid
Roundness2*	Few protrusions		Abundant protrusions
Perimeter ratio3*	Irregular outline		Regular outline
Deformity4*	Weak deformity		Strong deformity
Shape factor5*	Similar to convex contour		Dissimilar to convex contour
Branching	Unbranched		Branched

⁽¹⁾Aspect: Major axis/minor axis (of ellipse equivalent to the vessel).

⁽²⁾Roundness: Perimeter²/(4*π*area).

⁽³⁾Perimeter ratio: Convex contour perimeter/perimeter (convex contour: outline of the polygon best-fitting to the real shape).

⁽⁴⁾Deformity: Convex contour area-area (μm²).

⁽⁵⁾Shape factor: Matches the shape (including the centroids, the area, and information about the orientation) of the vessels and the convex contour (formula: max_i=1,2[│m_i^A-m_i^B│/│m_i^A│]; m_i^A/B=sign (h_i^A/B)· log(h_i^A); A/B=Hu moments of real contour/convex contour; í = seven Hu invariant).

^*All these parameters provide information about the degree of deviation from a round and regular blood vessel, using different approaches.