Table 1. Top 10 significantly enriched signaling pathways associated with the miRNAs specific for triple negative tumors.
KEGG pathway | p-value | #genes |
---|---|---|
PI3K-Akt signaling pathway | 2.43E-38 | 184 |
MAPK signaling pathway | 1.26E-29 | 137 |
Regulation of actin cytoskeleton | 1.25E-25 | 116 |
Endocytosis | 3.09E-25 | 109 |
Focal adhesion | 1.31E-24 | 116 |
Calcium signaling pathway | 6.45E-23 | 104 |
Wnt signaling pathway | 1.29E-21 | 93 |
RNA transport | 3.24E-18 | 81 |
Ubiquitin mediated proteolysis | 3.24E-18 | 83 |
Dopaminergic synapse | 1.27E-17 | 79 |