Figure 5. Relative changes in protein and mRNA levels across the treatment groups.

Western blotting was performed for specified target proteins, and a summary of densitometry analysis is presented. Relative band densities were compared to those of normal stroma, and those showing a fold change of >+1.25 were considered differentially expressed. Changes are shown for individual patients (each represented by coloured boxes), depicting the frequency of positive or negative change A. Similarly presented data based on the results of PCR-assays, depicting positive or negative changes in relative mRNA-levels for the same targets B. The raw data is shown in supplemental figures S3 and S4 respectively.