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. 2016 Mar 7;7(15):20381–20394. doi: 10.18632/oncotarget.7953

Figure 1. Low expression of miR-148a correlates with poor breast cancer patient prognosis.

Figure 1

(A) Expression levels of 29 miRNAs were profiled in MDA-MB-231 cells and normalized to levels in HMEC cells. (B) Expression of 6 miRNAs was determined in HMEC, MCF7-Ras, and MDA-MB-231 cells. Error bars indicate Standard Errors (n = 3). (C) and (D) Kaplan-Meier curves for overall survival for high and low expression of miRNAs, miR-148a (C) and miR-203 (D), in ER-HER2- subtype of breast cancer. Data was extracted from TCGA. P values were calculated with Log-rank (Mantel-Cox) test. Hazard ratios were calculated using the method of Mantel-Haenszel.