Table 2. The effects of ferulic acid (FA) on type A and type B monoamine oxidase activities in the spinal cord of sham and CCI mice.
Group | Dose(mg/kg) | Monoamine oxidase-A activity (nmol/30 min/mg protein) |
Monoamine oxidase-B activity (nmol/30 min/mg protein) |
---|---|---|---|
Sham + Vehicle | 59.3 ± 3.5 | 59.8 ± 4.9 | |
CCI + Vehicle | 92.6 ± 4.8### | 63.9 ± 3.4 | |
CCI + FA | 20 | 79.2 ± 5.4 | 60.8 ± 5.5 |
CCI + FA | 40 | 68.4 ± 5.2** | 61.6 ± 4.6 |
CCI + FA | 80 | 66.3 ± 5.5** | 54.4 ± 6.4 |
Table values are expressed as mean ± S.E.M. with units of ng/g for 8 mice in each group.
p < 0.001 vs. vehicle-treated sham mice.
p < 0.01 vs. vehicle-treated sham mice.