Table 1. Correction p-MEK1/SIRT1 expression and clinic-pathologic parameters of 87 hepatocellular carcinoma patients.

Variable	Total	p-MEK1/SIRT1 (High)	p-MEK1/SIRT1 (Low)	p-value
Age (years)
≤ 50	59	30	29	0.541
> 50	24	14	10
Gender
Female	15	10	5	0.331
Male	72	38	34
Tumor stage
I	5	1	4	< 0.001***
II	39	16	23
III	43	31	12
Tumor size (cm)
< 5	23	7	16	0.012*
≥ 5	59	36	23
Serum AFP level (ng/ml)
≤ 20	18	9	9	0.721
> 20	62	34	28
Tumor recurrence
−	45	22	23	0.227
+	42	26	16
Necrosis
+	38	17	21	0.395
++	26	19	7
+++	23	12	11
Capsular invasion
−	27	10	17	0.048*
+	35	22	13
++	25	16	9
Vascular invasion
−	25	7	18	< 0.001***
+	62	41	21
Interstitial hyperplasia of tumor
+	22	13	9	0.969
++	36	18	18
+++	29	17	12

Note: (1) *p < 0.05 ***p < 0.001 was considered statistically significant. (2) P-values were calculated with the Person chi-square test. (3) Total number < 87 due to missing data.