Skip to main content
. 2016 Mar 2;7(15):20669–20679. doi: 10.18632/oncotarget.7838

Figure 2.

Figure 2

a. Reactivity time courses for the decay of 100 μM S3I-201 in the presence of increasing concentrations of GSH (0.5, 1.0, 2.0, 5.0 10.0 mM) in a 100 mM HEPES buffer, pH 7.4 (fitted parameters available in Supplementary Table S4). b. Plot of the observed pseudo-first order rate constants (kobs) for the reaction of S3I-201 at increasing concentrations of GSH (0.5, 1.0, 2.0, 5.0, 10.0 mM) as a function of its concentration (fitted parameters available in Supplementary Table S5). c. Proposed operative mechanism of reaction between GSH and S3I-201 consistent with first order dependence in GSH concentration.