Table 1. Incidence of tumors and tumor histotype obtained in p53wt and p53EKO mice treated with DMBA and TPA.
Type of tumor | p53wt (%) | p53EKO (%) |
---|---|---|
Squamous papilloma | 16 (88,9) | 10 (19,6) |
Tricoepithelioma | 0 (0) | 3 (5,9) |
Basosquamous tumor | 0 (0) | 17 (33,3) |
Adenosquamous tumor | 0 (0) | 1 (2,0) |
Papillomas with microcarcinomas | 2 (11,1) | 2 (3,9) |
Poorly-differentiated SCC | 0 (0) | 18 (35,3) |
TOTAL: | 18 | 51 |