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. 2016 Aug 1;14(6):333–344. doi: 10.1089/adt.2015.688

Table 3.

α4β2 Agonist Potency

	EC₅₀, μM
Reference agonist	Day 1	Day 2	Average	Reference
A-85380	0.197	0.291	0.24	0.4^a
Acetylcholine	16.89	27.80	22.3	1.3 (HS); 75.3 (LS)^b
Cytisine	11.65	10.34	11.0	11.6^c
Nicotine	7.12	9.77	8.4	2.5^a
RJR 2403	4.21	3.47	3.8	10^a
Varenicline	2.33	1.48	1.9	4^a

^aRef.⁴⁶: FLIPR Ca-flux.

^bRef.²²: IWB, HS.

^cRef.⁴⁷: Manual patch clamp.

FLIPR, Fluorometric Imaging Plate Reader; HS, high sensitivity; IWB, IonWorks Barracuda; LS, low sensitivity.