TABLE 3.
Univariate analysis |
Multivariate analysis |
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---|---|---|---|---|---|---|
2DE geometric parameters | OR | 95% CI | P value | OR | 95% CI | P value |
Anterior tethering angle, ° (4CH view) | 1.10 | 1.00–1.22 | .061 | - | - | - |
Tethering height, mm (2CH view) | 5.04 | 0.94–26.99 | .059 | - | - | - |
Tethering area, cm2 (2CH view) | 3.05 | 1.25–7.46 | .015 | - | - | - |
Anterior tethering angle, ° (2CH view) | 1.09 | 1.00–1.18 | .053 | - | - | - |
PTA, ° (2CH view) | 1.18 | 1.05–1.34 | .008 | 1.17 | 1.04–1.32 | .010 |
3DE geometric parameters | ||||||
Septolateral diameter, mm | 1.00 | 0.86–1.17 | .975 | - | - | - |
Commissural width, mm | 0.98 | 0.88–1.10 | .772 | - | - | - |
Mitral transverse diameter, mm | 0.97 | 0.84–1.12 | .688 | - | - | - |
Mitral annular area, mm2 | 1.00 | 1.00–1.00 | .781 | - | - | - |
Annular circumference, mm | 1.01 | 0.96–1.06 | .846 | - | - | - |
Mitral valve tethering volume, mm3 | 1.00 | 1.00–1.00 | .069 | - | - | - |
Mitral valve tethering index | 2.48 | 1.19–5.17 | .015 | - | - | - |
Segmental tethering angle, ° | ||||||
A1 | 1.09 | 1.00–1.19 | .058 | - | - | - |
A2 | 1.05 | 0.99–1.12 | .094 | - | - | - |
A3 | 1.10 | 1.02–1.19 | .019 | - | - | - |
P1 | 1.07 | 0.99–1.16 | .076 | - | - | - |
P2 | 1.13 | 1.04–1.22 | .005 | - | - | - |
P3* | 1.28 | 1.11–1.49 | .001 | 1.28 | 1.11–1.49 | .001* |
2DE, 2-Dimensional echocardiography; OR, odds ratio; CI, confidence interval; 4CH, 4-chamber; 2CH, 2-chamber; PTA, posterior tethering angle; 3DE, 3-dimensional echocardiography.
When the univariate functional parameter “basal aneurysm/dyskinesis” (OR, 42.00; 95% CI, 4.35–405.13; P= .001) was added to the geometric 3DE analysis, multivariate analysis revealed preoperative P3TA (OR, 1.24; 95% CI, 1.07–1.45; P= .005) and basal aneurysm/dyskinesis (OR, 16.47; 95% CI, 1.34–202.74; P= .029) as independent predictors of IMR recurrence.