Table II.
Urinary paracetamol and p-aminophenol concentrations by pregnancy status, LIFE Study, 2005–2009.
| Biomarker (ng/ml) | % > LOQ | Pregnant | Not pregnant | Withdrew | P |
|---|---|---|---|---|---|
| Median (IQR) | Median (IQR) | Median (IQR) | |||
| Females, n | 334 | 50 | 86 | ||
| paracetamol (LOQ = 0.50 ng/ml) | 97 | 18.9 (6.49, 130) | 29.6 (5.75, 1301) | 20.2 (5.98, 253) | 0.75 |
| p-aminophenol (LOQ = 0.25 ng/ml) | 100 | 747 (305, 1282) | 649 (3145, 1793) | 939 (328, 1995) | 0.09 |
| Males, n | 313 | 48 | 78 | ||
| paracetamol (LOQ= 0.50 ng/ml) | 93 | 13.9 (5.25, 53.8) | 17.23 (6.54, 789) | 17.4 (6.19, 118) | 0.18 |
| p-aminophenol (LOQ = 0.25 ng/ml) | 100 | 979 (493, 1596) | 936 (508, 1476) | 978 (542, 1630) | 0.99 |
P-values were calculated using the nontransformed median in Kruskal–Wallis tests comparing urinary paracetamol and p-aminophenol concentrations across the three pregnancy status groups.
LOQ, limit of quantification; IQR, interquartile range.