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. 2016 Aug 19;31(9):2090–2097. doi: 10.1093/humrep/dew181

Figure 1.

Figure 1

Metabolic phenotype: (A) mice (n = 200, 50 per group) were on the high-fat/high-sugar (HF/HS) diet or a normal diet for 12 weeks and received subcutaneous, injections of co-enzyme Q10 (CoQ10, 22 mg/kg) or vehicle (Veh) for the latter 6 weeks. (B) Weekly weights (n = 50 per group) were obtained starting at 4 weeks until 16 weeks. (C) Prior to sacrifice at 16 weeks, body composition (n = 73) was assessed by EchoMRI. (D) Glucose levels (n = 50) were measured using venous tail blood after 4–5 h of fasting at 4 weeks, prior to diet exposure and again at 16 weeks. (E) Serum cholesterol (n = 40) concentration was obtained at 10 and 16 weeks. Values are represented as mean with error bars indicating+SEM. Statistical analyses were performed using Student's t-test or one-way ANOVA. *P < 0.05.