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. 2016 Aug 19;8(4):338–348. doi: 10.1093/jmcb/mjw009

Figure 6.

Figure 6

Plk1 phosphorylation of Kin1 modulates its ability to regulate ac-tub levels via HDAC6. (A and B) Ac-tub levels were determined 45 min after disruption of the MT cytoskeleton in MT regrowth assays in cells expressing GFP or GFP fused to indicated Kin1 mutants (A) ±tubacin (B). (C) A simplified schematic summarizes the interplay between Kin1, Plk1, and HDAC6 in their regulation of MT acetylation and stability. In all graphs shown, n ≥ 3, >250 cells were measured and error bars are ±SEM. P-values, t-test, *<0.05 and **<0.01.