Table II.
Comparison of levels of CVR, CVRI, eNOS, ET-1 and ETBR values in CMS and healthy controls.
| Group | No. of cases | CVR | CVRI | eNOS (μg/μl) | ET (μmol/l) | ET-RA/R (pg/ml) |
|---|---|---|---|---|---|---|
| CMS | 26 | 3.8±3.0 | 3.5±2.9 | 39.5±10.8 | 42.0±20.3 | 386.1±181.6 |
| Control | 23 | 6.4±6.9 | 7.1±7.5 | 38.3±13.9 | 41.9±17.9 | 312.3±138.1 |
| t-value | 2.336a | 3.084a | 0.474 | 0.039 | 2.317a | |
| P-value | 0.011 | 0.001 | 0.325 | 0.484 | 0.011 |
a
Significant difference, P<0.05. CVR, cerebrovascular reactivity; eNOS, endothelial nitric oxide synthase; ET, endothelin; ETBR, ET receptor B; CMS, chronic mountain sickness.