Figure 4.

Effect of ZSD on MSU crystal-induced NF-κB activation in the synovium of rats. The expression levels of cytoplasmic IκB and nuclear NF-κB p65 in synovial tissues from each treatment group were measured using western blot analysis. Representative bands are shown (left), and the relative band intensity ratio was analyzed (right). Data are presented as the mean ± standard deviation (n=6). ^**P<0.01, vs. control group; ^##P<0.01, vs. model group. C, cytoplasm; N, nuclear. ZSD, Zisheng Shenqi decoction; MSU, monosodium urate; Col, colchicine; NF-κB, nuclear factor-κB; IκB, inhibitor of NF-κB.