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Effects of Ang (1-7) (10−8 mol/l) and A779 (10−6 mol/l) on the GSIS from INS-1 cells in the presence of H2O2. Insulin secretion was markedly reduced (51.8%) by H2O2 treatment which was partly reversed by Ang (1-7) (34.1%). *P<0.05. Data are presented as the mean ± standard error of the mean (n=3). Ang (1-7), angiotensin (1-7); GSIS, glucose-stimulated insulin secretion; OD, optical density.
