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. 2016 Jul 29;14(3):2503–2510. doi: 10.3892/mmr.2016.5578

Table II.

Erythroid transcription factor miRNA levels in the negative control, overexpression and interference groups (means ± SD, n=9).

Group Normoxic
Hypoxic
HIF-1α GATA-1 GATA-2 NF-E2 HIF-1α GATA-1 GATA-2 NF-E2
Negative 1.77±0.43 3.57±0.05 39.20±5.10 31.44±8.20 7.40±1.21c 5.33±0.76c 34.11±4.01 78.13±13.68c
Overexpression 48.69±12.28a 4.48±0.61a 7.45±2.72a 34.37±13.33 31.79±5.65ac 7.73±0.76a,c 34.28±3.05c 55.62±18.74a
Interference 1.52±0.48b 3.29±0.73b 59.60±12.90a,b 16.56±2.29a,b 2.06±0.28 a–c 1.72±0.61a,b 98.91±25.84a–c 8.09±3.25a,b
F 58.569 5.023 41.498 4.369 90.048 71.638 24.160 27.960
P-value 0.000007 0.037090 0.000029 0.047209 0.000001 0.000003 0.000241 0.000138
a

Compared to the negative control group P<0.05;

b

compared to the overexpression group P<0.05;

c

compared to normoxia P<0.05. miRNA, microRNA; HIF-1α, hypoxia-inducible factor-1α; NF-E2, nuclear factor-erythroid 2.