Table 1.
Clinical characteristics of 857 allo-HSCT patients transplanted at MSKCC
Dates of transplant | May 1992 to July 2015 |
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Age (years) | 18 to 77, median 49 |
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Gender | Female 341 (40%), male 516 (60%) |
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Primary malignancy | NHL 242 (28%), AML 277 (32%), CML 48 (5.6%), MDS/MPD 71 (8.3%), ALL 74 (8.6%), CLL 41 (4.8%), Hodgkin disease 70 (8.2%), multiple myeloma 24 (2.8%), other hematological malignancies 16 (1.9%), other malignancies 8 (0.9%), non-malignant hematological disorders 22 (2.6%) |
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Graft source | Peripheral blood 497 (58%), cord blood 197 (23%), bone marrow 163 (19%) |
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Conditioning intensity | Standard intensity myeloablative 305 (36%), reduced intensity myeloablative 283 (33%), nonmyeloablative 268 (31%) |
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HLA matching | HLA identical 604 (70%), HLA mismatch 253 (30%) |
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Antibiotics for neutropenic fever | No antibiotics for neutropenic fever 474 (55%) |
Imipenem-cilastatin or piperacillin-tazobactam first-line 306 (36%) | |
Received imipenem-cilastatin only 6 (0.7%) | |
Received piperacillin-tazobactam only 183 (21%) | |
Received both 117 (14%) | |
Also received aztreonam or cefepime 106 (12%) | |
Aztreonam or cefepime first-line 77 (9%) | |
Received aztreonam only 18 (2.1%) | |
Received cefepime only 40 (4.7%) | |
Received both 19 (2.2%) | |
Also received imipenem-cilastatin 23 (2.7%) |