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. 2016 Jul 21;129:221–230. doi: 10.1007/s11060-016-2178-x

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 4 — Analysis of candidate biomarkers and correlation of candidate biomarkers with treatment response. Protein concentrations of previously published candidate biomarkers were measured in serum samples by ELISA (a, d) or immunonefolometry. b Thrombocyte counts were measured by a CD4000 impedance hematology analyzer. c Correlation with treatment response was determined by Cox regression (not shown) and group comparison. Fetuin-a protein concentrations were significantly different between good and poor response groups (p = 0.03)