Table 3.

Investigational products in clinical research

- Investigational Medicinal Products (IMPs) are registered or non-registered medicines. New chemical entities, but also the medicinal product in the comparative study group and placebo’s of the challenging agents are encountered as IMPs.

- Non-Investigational Medicinal Products (non-IMPs) are medicines that are not the subject of investigation but supportive to the trial. These can include rescue medication, medicinal products given as standard care, or substances that are meant to induce a physiological response that is necessary to assess the pharmacological action of the IMP.

Medical devices: will fall outside the scope of this paper.