Table 4.

Sensitivity coefficients of important nanoparticle-specific parameters (four experiments averages, <−0.3 or >0.3 bolded)

Parameter	Blood	Lungs	Liver	Spleen	Kidneys	Heart	Brain	GI tract	Urine	Feces
CLE fgi  a	−0.08	0.00	−0.65	−0.62	−0.64	−0.46	−0.17	−0.92	−0.66	0.08
M cap	0.86	0.01	−0.13	−0.09	−0.12	−0.07	−0.02	−0.01	−0.16	0.00
k ab0	−0.02	0.07	0.19	−0.75	0.14	0.10	0.02	0.00	−0.81	0.00
k giab	0.08	0.00	0.69	0.66	0.67	0.49	0.18	0.03	0.70	−0.04
k uagi	0.00	0.00	0.01	0.01	0.01	−0.23	−0.72	0.00	0.01	0.02
P	−0.05	0.00	0.52	0.49	0.48	0.34	0.12	0.04	−0.46	0.00
χ rest  b	−0.05	0.00	−0.39	−0.39	−0.36	−0.27	−0.08	−0.02	−0.41	0.00
fr ua	0.08	0.00	0.69	0.66	0.68	0.67	0.98	0.92	0.70	0.97
fr pul	0.06	0.76	0.42	0.42	0.43	0.42	0.00	0.05	0.44	0.00

^a Clearance rate from GI tract to feces

^b Permeability coefficient between blood to rest of the body