Fig. 1.

Kinetics of Crz1 recruitment to gene promoters upon high pH stress. a Time-course of accumulation of Crz1 at intergenic regions. The time-point at which the higher number of reads was accumulated at the peak region was identified for the 100 intergenic regions for which a given gene could be assigned (filled bars) and for the 52 divergent promoters (empty bars). b The ratio of the number of reads at the peak of each intergenic region at a given time and at time zero was calculated (fold-change) and the resulting values (expressed as log2) clustered using Cluster 3.0 (Euclidean distance, complete linkage) and represented with Java Treeview v1.1.6. The positions in the cluster of promoters corresponding to genes known to respond to calcineurin/Crz1 activation or for which evidence for in vitro or in vivo binding of Crz1 exists are represented at the right. c The time-course distribution of the number of reads at the Crz1 peak of recruitment is shown for diverse promoters of genes involved in glucose transport and phosphorylation