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Hits validation. 10-Point concentration-response curves of the seven FDA approved drugs that showed significant enhancement in the barrier function of the bEnd3 cells-based BBB model. The drugs were tested in the concentration range 0.065–20 μM to calculate compounds EC50s. The 10th point (20 μM) was eliminated from the curves due to toxicity. Data represent mean±SEM, n = 6 for each concentration.
