Table 2.

Sex-Stratified Association between Psychosocial Factors and CCA (n=894)

Psychosocial Measures	CCA Age adjusted model		CCA Multivariable* adjusted model		CCA ** MV+ diet/exercise adjusted
	Men	Women	Men	Women	Men	Women
Anger
Mean difference in 1-SD increase (95% CI)	0.013 (−0.006 – 0.032)	0.009 (−0.008 – 0.025)	0.013 (−0.005 – 0.032)	0.004 (−0.012 – 0.021)	0.009 (−0.010 – 0.029)	0.004 (−0.013 – 0.020)
p-value	0.19	0.30	0.16	0.60	0.33	0.65
Anxiety
Mean difference in 1-SD increase (95% CI)	0.023 (0.005 – 0.041)	−0.013 (−0.031 – 0.005)	0.022 (0.004 – 0.040)	−0.014 (−0.032 – 0.004)	0.023 (0.004 – 0.041)	−0.011 (−0.029 – 0.006)
p-value	0.01	0.15	0.02	0.12	0.02	0.19
Depression
Mean difference in 1-SD increase (95% CI)	0.024 (0.004 – 0.043)	−0.009 (−0.026 – 0.008)	0.022 (0.003 – 0.042)	−0.011 (−0.028 – 0.006)	0.019 (−0.001 – 0.039)	−0.011 (−0.028 – 0.006)
p-value	0.02	0.31	0.03	0.21	0.063	0.21
Current Stress
Mean difference in 1-SD increase (95% CI)	0.007 (−0.012 – 0.026)	0.024 (0.007 – 0.040)	0.005 (−0.014 – 0.024)	0.018 (0.002 – 0.035)	0.003 (−0.016 – 0.022)	0.018 (0.002 – 0.035)
p-value	0.48	0.01	0.62	0.03	0.73	0.03
6-Month Stress
Mean difference in 1-SD increase (95% CI)	0.010 (−0.010 – 0.029)	0.021 (0.005 – 0.038)	0.007 (−0.012 – 0.026)	0.018 (0.002 – 0.034)	0.006 (−0.013 – 0.025)	0.017 (0.001 – 0.034)
p-value	0.33	0.01	0.47	0.03	0.53	0.04
Hassle
Mean difference in 1-SD increase (95% CI)	0.010 (−0.010 – 0.030)	−0.005 (−0.021 – 0.010)	0.012 (−0.008 – 0.032)	−0.009 (−0.024 – 0.007)	0.012 (−0.007– 0.033)	−0.010 (−0.025 – 0.006)
p-value	0.33	0.50	0.24	0.27	0.23	0.20

^*Model adjusted for the traditional CVD risk factors - SBP, hypertension medication use, current smoking, BMI, diabetes, cholesterol ratio and education level

^**Model adjusted for factors above + dietary pattern and physical activity