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. 2016 Feb 11;31(4):414–422. doi: 10.1007/s12291-016-0557-x

Table 2.

Analytical recoveries of organic acids from spiked urine sample extracted by liquid–liquid extraction and solid phase extraction

Compound Liquid–liquid extraction Solid phase extraction
Mean recovery (%) CV (%) Mean recovery (%) CV (%)
Propionylglycine 52.08 8.8 61.12 10.6
Butrylglycine 81.26 6.2 81.46 6.2
Isovalerylglycine 63.86 11.8 65.06 6.2
3-Methyl crotonylglycine 75 12.4 75.96 10.6
Tiglylglycine 65.9 14.5 77.16 16.2
Hexanoylglycine 44.82 8.9 53.7 8.3
Methylmalonic acid 99.0 9.0 99.6 2.7
Fumaric acid 75.25 7.9 96.25 18.5
Succinylacetone 67.75 10.6 93.4 16.2
Glutaric acid 100.5 6.8 99.6 8.3
Adipic acid 83.25 6.4 101 18.4
Sebacic acid 98.25 3.6 93.4 16.6
Suberic acid 105.75 5.4 111.0 11.5
2-Ketoisocaproic acid 70.6 9.8 68.9 10.9
Mean 77.4 8.7 84.1 11.5