Table 6.
Correlations between neuropsychological tests results and fatigue measures, including multiple regression analysis of correlations between fatigue measures (FSS/FSS-5, MFIS), neuropsychological tests (SDMT, PASAT) and age, disease duration and progression of disability (MSSS) (R–Pearson’s correlation coefficient)
| FSS | FSS-5 | MFIS | MFISmod | Physical subscale MFISmod |
Cognitive subscale MFISmod |
|
|---|---|---|---|---|---|---|
| SDMT |
R = −0.38 p = 0.00001 |
R = −0.38 p = 0.00001 |
R = −0.42 p = 0.00001 |
R = −0.42 p = 0.0001 |
R = −0.38 p = 0.0003 |
R = −0.33 p = 0.002 |
| PASAT |
R = −0.30 p = 0.004 |
R = −0.32 p = 0.005 |
R = −0.39 p = 0.00001 |
R = −0.33 p = 0.002 |
R = −0.24 p = 0.024 |
R = −0.37 p = 0.0005 |
| SDMT = f(FSS, age, disease duration, MSSS) N = 86, R = 0.53, R 2 = 0.28, adjusted R 2 = 0.26, p = 0.00000 | |||
|---|---|---|---|
| Beta | B | p | |
| Disease duration | −0.389 | −0.730 | 0.00010 |
| MSSS | −0.439 | −2.73 | 0.00001 |
| SDMT = f(MFIS, age, disease duration, MSSS) N = 86, R = 0.57, R 2 = 0.32, adjusted R 2 = 0.30, p = 0.00000 | |||
|---|---|---|---|
| Beta | B | p | |
| MFIS | −0.234 | −0.198 | 0.0240 |
| Disease duration | −0.305 | −0.572 | 0.00302 |
| MSSS | −0.358 | −2.23 | 0.00052 |
| PASAT = f(FSS, age, disease duration, MSSS) N = 86, R = 0.30, R 2 = 0.09, adjusted R 2 = 0.08, p = 0.00442 | |||
|---|---|---|---|
| Beta | B | p | |
| FSS | −0.304 | −2.06 | 0.00442 |
| PASAT = f(MFIS, age, disease duration, MSSS) N = 86, R = 0.39, R 2 = 0.15, adjusted R 2 = 0.14, p = 0.00022 | |||
|---|---|---|---|
| Beta | B | p | |
| MFIS | −0.388 | −0.290 | 0.00022 |
Bold values indicate p < 0.05 which are statistically significant