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Flow diagram for the study patients. ESD: endoscopic submucosal dissection; EAC: esophageal adenocarcinoma; LGIN: low-grade intraepithelial neoplasia; ESCC: esophageal squamous cell carcinoma; and HGIN: high-grade intraepithelial neoplasia. aMain including leiomyoma, stromal tumor, inflammation, and epithelial hyperplasia.
