Table 1.

Different types of transgenic zebrafish used to the nanoparticle/chemical toxicity study

	Nanoparticle/chemicals used	Transgenic zebrafish type that is used to understand the nanoparticle toxicity	Remark	References
1.	TiO2, SiO2, CuO	Transgenic (nacre/fli1:EGFP) zebrafish	Transgenic fish exposed to TiO2,SiO2, CuO particles with a concentration of 0.01, 1 and 100 μg/ml concentrations and noted that CuO nanoparticles inhibit vasculogenesis	[140]
2.	TiO2, C60(OH)24) (hydroxylated fullerenes/)	Gene expression of zebrafish embryos	Circadian rhythm gene/(s) deregulated by nanoparticles	[141]
3.	TiO(2)	ARE transgenic zebrafish	Exposure TiO(2) nanoparticle cause death of zebrafish embryos	[137]
4.	Small molecules	Transgenic embryos expressing green fluorescent protein in myocardium	Small molecule alter in heart rate of transgenic embryos	[142]
5.	Metal oxide nanoparticles such as CuO, ZnO, NiO, and Co(3)O(4))	hsp70:eGFP transgenic zebrafish larvae	CuO, ZnO, and NiO may augmented expression of hsp70:eGFP in transgenic zebrafish larvae	[136]
6.	Inorganic nanorods	Transgenic (fli1a:EGFP) zebrafish embryos	This study noted that—ROS mediated angiogenesis in transgenic zebrafish embryo using inorganic nanorods	[143]
7.	Cadmium selenium (CdSe) quantum dots (QDs) coated with mercaptopropionic acid (MPA)	FLI-1 transgenic zebrafish larvae	abnormal vascularization occoured in transgenic zebrafish larvae	[144]
8	Mesoporous silica nanoparticles (MSNPs)	lysC:DsRED2 transgenic embryos	It can be used to deliver bioactive compounds	[145]