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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: J Am Acad Dermatol. 2016 Sep;75(3):481–493.e8. doi: 10.1016/j.jaad.2016.04.066

Figure 6. Relative abundance of major phyla in control and AD lesional and nonlesional sites at baseline and after treatment.

Figure 6

Analysis performed at sequence depth > 4,800 reads for each of the 249 specimens. At baseline (Panels A–E), all sites showed a mixture of five major phyla but for AD lesional skin, Firmicutes dominated with relative absence of Bacteriodetes (Panels A,C). Nonlesional skin showed intermediate patterns (Panels B, D). After the treatment period (Panels F–J), controls were largely unchanged, as expected (Panel J), but all AD sites normalized (Panel F) with decreased Firmicutes, and Bacteroidetes reappearing. Control subjects: E,J; TCS + bleach treatment group: lesional sites: A,J; nonlesional sites; B,G; TCS alone group: lesional sites: C,H; nonlesional sites: D,I.