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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Arthritis Rheumatol. 2016 Jul;68(7):1751–1757. doi: 10.1002/art.39638

Figure 1.

Figure 1

Point-of-care Raman spectroscopy (POCRS). The POCRS system consists of 2 parts: a syringe microfiltration kit for isolating and collecting arthritic crystals from synovial fluid (a–c) and a shoebox-sized optoelectromechanical system for acquiring diagnostic signals (d and e). To use the system, synovial fluid is loaded in a glass vial with digestive enzymes (a). After 30 minutes of digestion at 40°C, the uric acid–supplemented buffer (b) is used to dilute the digested synovial fluid. Following dilution, the synovial fluid is transferred into a standard syringe (c) and pushed through the disposable microfiltration cartridge for crystal collection. After microfiltration, the cartridge is directly inserted into the optoelectromechanical system (d) for diagnostic signal acquisition (e).