Table 1.
Baseline characteristics of the OA LIFE subset of subjects utilized for the biomarker study.
| Total N=169 |
PCST only N=42 |
BWM only N=42 |
PCST+BWM N=49 |
SC N=36 |
P value* | ||
|---|---|---|---|---|---|---|---|
| Sex, N (% female) | 140 (83%) | 30 (72%) | 37 (88%) | 44 (90%) | 29 (81%) | 0.0927 | |
| Non-white, N (%) | 68 (40%) | 17 (40%) | 16 (38%) | 20 (41%) | 15 (42%) | 0.9896 | |
| Age, mean (CI) in years | 58.7 (57.2, 60.2) | 59.1 (55.5, 62.8) | 58.9 (56.0, 61.7) | 58.3 (55.5, 61.1) | 58.5 (55.1, 61.9) | 0.9780 | |
| [Range] | [37–83] | [37–82] | [41–76] | [39–83] | [44–79] | ||
| Weight, mean (CI) in lbs | 205.7 (200.8, 210.7) | 213.0 (201.9, 224.0) | 202.0 (191.9, 212.2) | 203.5 (193.9, 213.0) | 204.7 (195, 214.4) | 0.5633 | |
| [Range] | [134–297] | [153–297] | [137–280] | [134–278] | [138–260] | ||
| BMI, mean (CI) in kg/m2 | 34.1 (33.4, 34.8) | 35.0 (33.7, 36.3) | 33.5 (32.1, 34.8) | 34.0 (32.7, 35.4) | 33.9 (32.4, 35.4) | 0.4199 | |
| [Range] | [25–43] | [27–42] | [25–42] | [25–42] | [27–43] | ||
| Kellgren-Lawrence grade, % grade | 7/15/18/ | 6/8/18 | 6/20/12 | 6/18/17 | 11/13/26 | 0.4813 | |
| 0/1/2/3/4/TKR | 38/18/3 | 46/18/4 | 43/17/2 | 35/20/3 | 28/18/4 | ||
| WOMAC | Pain | 43.5 (40.4, 46.6) | 44.2 (36.7, 47.7) | 42.1 (36.7, 47.7) | 44.3 (38.3, 50.4) | 42.9 (35.1, 50.7) | 0.9326 |
| Stiffness | 54.8 (51.0, 58.5) | 53.5 (45.9, 61.2) | 49.9 (42.7, 57.2) | 60.1 (53.5, 66.6) | 54.6 (45.2, 64.0) | 0.2281 | |
| Physical Function | 45.7 (42.6, 48.9) | 46.5 (40.3, 52.8) | 42.7 (37.6, 47.8) | 46.8 (40.5, 53.2) | 46.9 (38.3, 55.5) | 0.7785 | |
| AIMS | Pain | 5.4 (5.1, 5.7) | 5.5 (5.0, 6.0) | 5.1 (4.6, 5.6) | 5.5 (5.0, 6.1) | 5.6 (4.8, 6.3) | 0.6258 |
| Psychological Disability | 2.9 (2.7, 3.1) | 2.9 (2.4, 3.3) | 3.1 (2.5, 3.7) | 2.7 (2.2, 3.1) | 3.0 (2.5, 3.5) | 0.7320 | |
| Physical Disability | 1.6 (1.4, 1.7) | 1.7 (1.3, 2.0) | 1.3 (0.9, 1.6) | 1.6 (1.3, 2.0) | 1.7 (1.3, 2.1) | 0.1665 | |
PCST = pain coping skills training; BWM= behavioral weight management; SC = Standard Care
Data shown as Mean with 95% Confidence Intervals
*
P-values determined by non-parametric 1-way ANOVA (Kruskal-Wallis test)