The similarity index and the angular dispersion index are plotted here for three different subjects for our proposed self-referenced reconstruction, for varying numbers of diffusion directions, Nd. Both mean and standard deviation values are shown. (a) Similarity index values decreased as the number of directions decreased, but remained high (~85%) even for the lowest number of direction, Nd = 32. (b,c) The mean angular dispersion index remained below about 13 ° even for the maximum-acceleration scenario considered here, and even in voxels featuring fiber crossings.